Dupuytren Disease-Dupuytren Disease Comp Review 2017

Video Transcription

Video Summary

This video is a lecture on Dupuytren's disease, a progressive hand deformity. The lecturer provides important facts about the genetics, pathophysiology, clinical presentation, and treatment options for the disease. Dupuytren's disease has a clear genetic predisposition, especially in European white males, and is rare in other ethnicities. The disease is characterized by myofibroblast proliferation and a conversion of collagen matrix. Risk factors include increasing age, male sex, smoking, trauma, and certain medical conditions. Surgical treatment options include needle aponeurotomy, limited fasciectomy, and radical fasciectomy. The newly introduced collagenase called Xyaflex is also mentioned. Results and recurrence rates vary depending on the treatment option used. The lecture emphasizes the importance of patient education and informed consent process, as Dupuytren's disease is a progressive condition and treatment is palliative, not curative. The lecture concludes with suggestions for best treatment options and possible adjunct therapies, as well as a mention of potential complications and flare reactions associated with the disease.

Keywords

Dupuytren's disease

hand deformity

genetics

treatment options

collagenase

recurrence rates